KMID : 0363220080460101387
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Korean Journal of Dermatology 2008 Volume.46 No. 10 p.1387 ~ p.1390
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A Case of Squamous Cell Carcinoma with Nodal Metastasis Confirmed by Sentinel Lymph Node Biopsy
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Chi Seong-Geun
Kim Ho-Youn Park Byung-Cheol Lee Seok-Jong Choe Yoon-Seok Kim Byung-Soo Kim Do-Won
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Abstract
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Cutaneous squamous cell carcinoma (SCC) is the second most common skin cancer and the majority of such
patients can be easily treated with a relatively low risk of recurrence and metastasis. However, there are subgroups
of SCC that are at a higher risk, depending on patient¡¯s or tumor¡¯s characteristics. A greater part of the metastases
from these high-risked SCCs spread towards the regional lymph nodes, whereas distant metastases are relatively
uncommon. Early identification of nodal metastasis can allow the selective and timely inclusion of possible
high-risked SCC patients into more aggressive treatments and meticulous follow-up protocols for achieving potential
survival benefit. Therefore, sentinel lymph node biopsy (SLNB) is popular in the management of malignant
melanoma, and it may also be useful to detect regional metastasis of high-risked SCCs. This procedure could also
spare node-negative patients the morbidity of unnecessary additional therapy, like elective lymph node dissection. We
report herein on a case of SCC with regional nodal metastasis, which is confirmed by SLNB.
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KEYWORD
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Nodal metastasis, Sentinel Lymph node biopsy, Squamous cell carcinoma
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